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Mitochondrial Mechanisms of LRRK2 G2019S Penetrance

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The initial dose of HM30-tesirine maintained tumour volumes close to their pre-treatment size 8 days post-treatment (78 31 mm 3 ), whereas control and cisplatin-treated tumours had reached 518 130 mm 3 and 199 72 mm 3 , respectively by this time ( n = 36 mice

Although serum albumin levels showed a slight but statistically significant decrease (p=0.001), this change may reflect minor alterations in protein metabolism or systemic inflammation, with limited clinical relevance